Specific Areas of Research Expertise
- Development and validation of novel biomaterial-based technologies for treating neurological disorders
- Stem cell technologies, including adult stem cells and induced pluripotent stem cells, and the application of these technologies to brain and spinal cord repair
- The role of neuroinflammation, the endocannabinoid system, endoplasmic reticulum stress, neurotrophic factors, heat shock proteins and histone deacetylase complex in neurological and psychiatric disorders
- Pain research from bench to bedside through the Centre for Pain Research
- Development and validation of novel and highly-relevant animal models of neurological and psychiatric disorders
- Expertise in behavioural evaluation of motor, cognitive, affective and sensory function in animal models and in patients
- Clinical neuroimaging: structural, diffusion and functional MRI
- SNP genotyping, genome-wide association studies, nextgeneration sequencing, copy number variant analysis pertaining to schizophrenia and other nervous system disorders
- Cognitive neuroscience
- Psychological (e.g. cognitive behavioural) interventions for improved management of neurological and psychiatric disorders
Technical Capabilities
- Clinical neuroimaging: MRI and PET
- Clinical EEG/EMG neurophysiology
- Neuropsychological and clinical assessment of cognition
- Clinical and preclinical genomics: genotyping and next-generation sequencing
- Generation of human pluripotent stem cells (iPSc)
- Preclinical disease models: anxiety, autism, depression, multiple sclerosis, Parkinson’s disease, pain, spinal cord injury, stress, stroke
- Preclinical behavioural neuroscience
- In vitro disease models: Huntington’s disease, neurodegeneration, neuroinflammation, Parkinson’s disease, stroke
- In vivo microdialysis
- Proteomics/lipidomics: mass spectrometry
- Microscopy (incl. electron and confocal), histology, autoradiography and neurostereology
- Cell/Enzyme based assays
- Molecular biology (e.g. Western blot, RT-qPCR)
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